Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.39 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053858 | 1.00 | MEN1 (0.43) | MEN1KMT2AALDH1A1ALOX12RAB9A | |
| SCHEMBL6545781 | 0.94 | MEN1 (0.46) | MEN1KMT2AALDH1A1ALOX12RAB9A | |
| SCHEMBL7054234 | 0.94 | MEN1 (0.46) | MEN1KMT2AALDH1A1ALOX12RAB9A | |
| SCHEMBL7051474 | 0.91 | MEN1 (0.42) | MEN1KMT2AALDH1A1ALOX12RAB9A | |
| SCHEMBL6546525 | 0.91 | MEN1 (0.42) | MEN1KMT2AALDH1A1ALOX12RAB9A | |
| SCHEMBL7054846 | 0.90 | MEN1 (0.46) | MEN1KMT2AALDH1A1RAB9AHDAC1 | |
| SCHEMBL6545634 | 0.90 | MEN1 (0.46) | MEN1KMT2AALDH1A1RAB9AHDAC1 | |
| SCHEMBL6545859 | 0.83 | MAPT (0.46) | MEN1KMT2AALDH1A1RAB9AHDAC1 | |
| SCHEMBL6546015 | 0.82 | MEN1 (0.52) | MEN1KMT2AALDH1A1ALOX12RAB9A | |
| SCHEMBL7052138 | 0.82 | MEN1 (0.52) | MEN1KMT2AALDH1A1ALOX12RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257265-B1 | USE OF 2-PHENYLENE DIAMINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | BIOAGENCY AG (DE) | 2004-01-21 | — | — | EP | disclosed |
| EP-1303258-A1 | NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE | AstraZeneca AB (SE) | 2003-04-23 | — | — | EP | disclosed |
| EP-0936208-B1 | Process for the preparation of 2-cycloalkenones | BASF AG (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002003958-A1 | NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE | ASTRAZENECA AB (SE) | 2002-01-17 | — | — | WO | disclosed |
| EP-0936208-A1 | Process for the preparation of 2-cycloalkenones | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-18 | — | — | EP | disclosed |