Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 18/20 | 0.62 |
| ▸ | SRC | P12931 | 10/20 | 0.62 |
| ▸ | SYK | P43405 | 10/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545938 | 0.92 | GSK3A (0.65) | GSK3ASRCSYKMAPK14CYP3A4 | |
| SCHEMBL6643809 | 0.92 | MAPK14 (0.55) | GSK3ASRCSYKMAPK14CYP3A4 | |
| SCHEMBL6545585 | 0.91 | MAPK14 (0.64) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL6545700 | 0.90 | GSK3A (0.55) | GSK3ASRCSYKMAPK14CYP3A4 | |
| SCHEMBL6305196 | 0.89 | MAPK14 (0.75) | GSK3ASRCSYKMAPK14CYP3A4 | |
| SCHEMBL6298580 | 0.88 | GSK3A (0.69) | GSK3ASRCSYKMAPK14CYP3A4 | |
| SCHEMBL6546195 | 0.87 | GSK3A (0.63) | GSK3ASRCSYKMAPK14CYP3A4 | |
| SCHEMBL6643837 | 0.87 | GSK3A (0.67) | GSK3ASRCSYKMAPK14CYP3A4 | |
| SCHEMBL23967439 | 0.86 | GSK3A (0.67) | GSK3ASRCSYKMAPK14CYP3A4 | |
| SCHEMBL16138970 | 0.86 | GSK3A (0.67) | GSK3ASRCSYKMAPK14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381592-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-01-21 | — | — | EP | claimed |
| WO-2002083628-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | claimed |
| EP-1392661-A1 | DIARYLUREA DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1381592-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002092576-A1 | DIARYLUREA DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-11-21 | — | — | WO | disclosed |
| WO-2002083628-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | disclosed |