Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.61 |
| ▸ | SRC | P12931 | 16/20 | 0.61 |
| ▸ | GSK3A | P49840 | 14/20 | 0.61 |
| ▸ | SYK | P43405 | 12/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545897 | 0.91 | MAPK14 (0.59) | MAPK14SRCGSK3ASYK | |
| SCHEMBL6545999 | 0.91 | GSK3A (0.71) | MAPK14SRCGSK3ASYK | |
| SCHEMBL6545890 | 0.90 | GSK3A (0.61) | MAPK14SRCGSK3ASYK | |
| SCHEMBL6545687 | 0.89 | MAPK14 (0.58) | MAPK14SRCGSK3ASYK | |
| SCHEMBL6546930 | 0.88 | MAPK14 (0.63) | MAPK14SRCGSK3ASYK | |
| SCHEMBL6546655 | 0.88 | GSK3A (0.61) | MAPK14SRCGSK3ASYK | |
| SCHEMBL6547592 | 0.87 | GSK3A (0.60) | MAPK14SRCGSK3ASYK | |
| SCHEMBL6546404 | 0.87 | MAPK14 (0.63) | MAPK14SRCGSK3ASYK | |
| SCHEMBL6546312 | 0.86 | SRC (0.60) | MAPK14SRCGSK3ASYK | |
| SCHEMBL6546880 | 0.86 | GSK3A (0.56) | MAPK14SRCGSK3ASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381592-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-01-21 | — | — | EP | claimed |
| WO-2002083628-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | claimed |