Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 1/20 | 1.00 |
| ▸ | MMP3 | P08254 | 7/20 | 0.63 |
| ▸ | MMP8 | P22894 | 7/20 | 0.63 |
| ▸ | MMP9 | P14780 | 6/20 | 0.63 |
| ▸ | KARS1 | Q15046 | 3/20 | 0.62 |
| ▸ | RXRA | P19793 | 1/20 | 0.62 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 1/20 | 0.62 |
| ▸ | RXRB | P28702 | 1/20 | 0.62 |
| ▸ | RXRG | P48443 | 1/20 | 0.62 |
| ▸ | POLA1 | P09884 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ecabet SCHEMBL8614405 | 1.00 | NR1I2 (1.00) | NR1I2OPRK1MMP3MMP8MMP9 | |
| Ecabet SCHEMBL373030 | 1.00 | NR1I2 (1.00) | NR1I2OPRK1MMP3MMP8MMP9 | |
| Ecabet SCHEMBL29727401 | 1.00 | NR1I2 (1.00) | NR1I2OPRK1MMP3MMP8MMP9 | |
| Ecabet SCHEMBL10938701 | 0.99 | NR1I2 (0.98) | NR1I2OPRK1MMP3MMP8MMP9 | |
| Ecabet SCHEMBL10937325 | 0.99 | NR1I2 (0.98) | NR1I2OPRK1MMP3MMP8MMP9 | |
| Ecabet SCHEMBL10935989 | 0.99 | NR1I2 (0.98) | NR1I2OPRK1MMP3MMP8MMP9 | |
| Ecabet SCHEMBL437091 | 0.99 | NR1I2 (0.98) | NR1I2OPRK1MMP3MMP8MMP9 | |
| Ecabet SCHEMBL10937322 | 0.99 | NR1I2 (0.98) | NR1I2OPRK1MMP3MMP8MMP9 | |
| Ecabet SCHEMBL7615516 | 0.99 | NR1I2 (0.98) | NR1I2OPRK1MMP3MMP8MMP9 | |
| Ecabet SCHEMBL10938694 | 0.99 | NR1I2 (0.98) | NR1I2OPRK1MMP3MMP8MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380294-A1 | PREVENTIVE/REMEDIAL AGENT FOR INFLAMMATORY DISEASE IN ORAL-CAVITY MUCOSA AND THE LIKE | TANABE SEIYAKU CO., LTD. (JP) | 2004-01-14 | — | — | EP | disclosed |