Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.64 |
| ▸ | PDE4A | P27815 | 18/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793134 | 0.88 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7786846 | 0.88 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7786662 | 0.88 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7472625 | 0.88 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7409643 | 0.88 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7786677 | 0.88 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4D | |
| Ammonia Solution, Strong SCHEMBL7390267 | 0.88 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7387551 | 0.87 | PDE4B (0.67) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7318584 | 0.87 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7385992 | 0.87 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420011-A1 | Compounds usefulfor treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1380571-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-14 | — | — | EP | disclosed |
| EP-0919544-B1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORP (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-0633776-B1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2001-05-09 | — | — | EP | disclosed |
| EP-0919544-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-02 | — | — | EP | disclosed |
| EP-0714293-A4 | 3-CYANO-3-(3,4-DISUBSTITUTED)PHENYLCYCLOHEXYL-1-CARBOXYLATES | SMITHKLINE BEECHAM CORP (US) | 1999-04-07 | — | — | EP | disclosed |
| US-5643946-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| US-5614540-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| US-5602157-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| US-5552438-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0714293-A1 | 3-CYANO-3-(3,4-DISUBSTITUTED)PHENYLCYCLOHEXYL-1-CARBOXYLATES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995003794-A1 | 3-CYANO-3-(3,4-DISUBSTITUTED)PHENYLCYCLOHEXYL-1-CARBOXYLATES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-09 | — | — | WO | disclosed |
| EP-0633776-A4 | — | — | 1995-01-25 | — | — | EP | disclosed |
| EP-0633776-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993019749-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |