Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 6/20 | 0.59 |
| ▸ | ITGB6 | P18564 | 5/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.59 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6806496 | 0.94 | ITGAV (0.55) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL6545825 | 0.94 | ITGAV (0.56) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL6545508 | 0.89 | ITGAV (0.57) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL6546463 | 0.89 | ITGAV (0.58) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| Trifluoroacetic Acid SCHEMBL6806766 | 0.89 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL6806500 | 0.86 | ITGAV (0.46) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL6545847 | 0.86 | ITGAV (0.61) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL6545174 | 0.86 | ITGAV (0.61) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL6545271 | 0.86 | ITGAV (0.61) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| Trifluoroacetic Acid SCHEMBL6810305 | 0.85 | ITGAV (0.53) | ITGAVITGB6ITGB3ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142877-A1 | Ligands of the $g(a)v$g(b)6 integrin | MERCK PATENT GMBH (DE) | 2004-07-22 | — | — | US | claimed |
| US-20040142877-A1 | Ligands of the $g(a)v$g(b)6 integrin | MERCK PATENT GMBH (DE) | 2004-07-22 | — | — | US | disclosed |
| EP-1379495-A2 | LIGANDS OF THE ALPHA-V-BETA 6 INTEGRIN | MERCK PATENT GmbH (DE) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002083627-A2 | LIGANDS DES INTEGRINS AVSS6 | MERCK PATENT GMBH (DE) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142877-A1 | Ligands of the $g(a)v$g(b)6 integrin | ITGB6, ITGAV, ITGB1 | ITGAV 2/4885ITGB6 1/4885ITGB3 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.