Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 19/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.63 |
| ▸ | SRC | P12931 | 4/20 | 0.57 |
| ▸ | SYK | P43405 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840006 | 0.87 | GSK3A (0.58) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6545672 | 0.86 | MAPK14 (0.59) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6546256 | 0.85 | GSK3A (0.69) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6547073 | 0.85 | MAPK14 (0.58) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6546910 | 0.81 | GSK3A (0.81) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6546066 | 0.80 | GSK3A (0.77) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6545784 | 0.78 | GSK3A (0.69) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6298782 | 0.77 | GSK3A (0.74) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6545966 | 0.77 | GSK3A (0.74) | GSK3AMAPK14SRCSYK | |
| SCHEMBL16829341 | 0.77 | GSK3A (1.00) | GSK3AMAPK14SRCSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381592-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-01-21 | — | — | EP | claimed |
| WO-2002083628-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | claimed |
| EP-1381592-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002083628-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | disclosed |