Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RHOC | P08134 | 1/20 | 0.32 |
| ▸ | RHOA | P61586 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549101 | 0.98 | HTT (0.34) | HTTGAAALOX15HSD17B10ALDH1A1 | |
| SCHEMBL6548184 | 0.97 | GAA (0.34) | HTTGAAALOX15HSD17B10ALDH1A1 | |
| SCHEMBL6547985 | 0.88 | HTT (0.34) | HTTRHOCRHOAFFAR1FFAR4 | |
| SCHEMBL3185522 | 0.85 | HTT (0.37) | HTTGAAALOX15HSD17B10RAB9A | |
| SCHEMBL3185519 | 0.85 | HTT (0.37) | HTTGAAALOX15HSD17B10RAB9A | |
| SCHEMBL8011673 | 0.85 | HTT (0.40) | HTTRHOCRHOAFFAR1CYP2C9 | |
| SCHEMBL6548903 | 0.84 | HTT (0.41) | HTTGAAALOX15HSD17B10RAB9A | |
| SCHEMBL8025900 | 0.83 | HTT (0.40) | HTTGAARHOCRHOAFFAR1 | |
| SCHEMBL8655977 | 0.82 | PPARA (0.42) | HTTALDH1A1RHOCRHOAFFAR1 | |
| SCHEMBL8406151 | 0.82 | FFAR4 (0.44) | HTTFFAR1CYP2C9SCN5AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975586-B1 | OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2004-12-01 | — | — | EP | claimed |
| EP-0975586-B1 | OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-6437184-B1 | INSECTICIDES, ACARICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-08-20 | — | — | US | disclosed |