Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.80 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547705 | 1.00 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL13676582 | 1.00 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7037452 | 0.92 | ADRB3 (0.85) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7040917 | 0.90 | ADRB3 (0.82) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7675887 | 0.89 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7674992 | 0.89 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7678634 | 0.89 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7670221 | 0.89 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7674986 | 0.89 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7043995 | 0.89 | ADRB3 (0.80) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659737-B1 | Catecholamine surrogates useful as beta 3 agonists | BRISTOL MYERS SQUIBB CO (US) | 2003-03-26 | — | — | EP | claimed |
| EP-0659737-A2 | Catecholamine surrogates useful as B3 agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-28 | — | — | EP | claimed |
| JP-7206806-A | — | — | None | — | — | JP | disclosed |
| EP-1382333-A2 | Use of beta 3 adrenergic receptor agonists in the treatment of dysuria | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-21 | — | — | EP | disclosed |
| EP-0659737-B1 | Catecholamine surrogates useful as beta 3 agonists | BRISTOL MYERS SQUIBB CO (US) | 2003-03-26 | — | — | EP | disclosed |
| US-6495546-B1 | SUCH AS 1-(N-BENZYL-N-(3-METHOXY-6,7,8,9-TETRAHYDRO-5H-BENZO-CYCLOHEPTEN-6-YL)AMINO)-3-PHENOXY-2-PROPANOL; ADRENERGIC RECEPTOR AGONISTS; ANTIULCEROUS, LIPOLYTIC, ANTIURINARY INCONTINENCE AND ANTIPOLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1070046-A1 | PROPANOLAMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051564-A1 | PROPANOLAMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-14 | — | — | WO | disclosed |
| JP-H07206806-A | CATECHOLAMINE SURROGATE USEFUL AS BETA3-AGONIST | BRISTOL MYERS SQUIBB CO | 1995-08-08 | — | — | JP | disclosed |
| EP-0659737-A2 | Catecholamine surrogates useful as B3 agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |