Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6548004 | 0.89 | HTT (0.35) | HTTCA9PPARG | |
| SCHEMBL6548842 | 0.89 | HRH3 (0.43) | HTTMAOAMAOBCCR5MAPT | |
| SCHEMBL6549405 | 0.89 | NPC1 (0.35) | HTTMAOAMAOBCCR5MAPT | |
| SCHEMBL6549004 | 0.88 | NPC1 (0.35) | HTTMAOAMAOBCCR5MAPT | |
| SCHEMBL6547693 | 0.86 | HTT (0.41) | HTTMAOAMAOBCA9MAPT | |
| SCHEMBL6548809 | 0.86 | HTT (0.33) | HTTMAOAMAOBCCR5MAPT | |
| SCHEMBL6547607 | 0.86 | HTT (0.33) | HTTMAOAMAOBCCR5MAPT | |
| SCHEMBL6549819 | 0.86 | MAOB (0.51) | HTTMAOAMAOBMAPTHRH3 | |
| SCHEMBL6548880 | 0.85 | HTT (0.41) | HTTCA9MAPTMEN1KMT2A | |
| SCHEMBL6548903 | 0.85 | HTT (0.41) | HTTCA9MAPTLMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975586-B1 | OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2004-12-01 | — | — | EP | claimed |