SCHEMBL6550035

SCHEMBL6550035

CCOC(COc1c(C)cc(OCC=C(Cl)Cl)cc1CC)=NOCC=C(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548998 0.89 HTT (0.34) HTTLMNA
SCHEMBL6547474 0.88 HTT (0.31) HTT
SCHEMBL6547835 0.88 HTT (0.36) HTT
SCHEMBL6549949 0.84 HTT (0.33) HTT
SCHEMBL7627952 0.83 HTT (0.34) HTT
SCHEMBL6549907 0.82 HTT (0.30) HTT
SCHEMBL6549420 0.82 HTT (0.36) HTT
SCHEMBL6547902 0.82 HTT (0.33) HTT
SCHEMBL6547629 0.82 HTT (0.33) HTT
SCHEMBL6550079 0.81 HTT (0.32) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed