SCHEMBL6550154

SCHEMBL6550154

NOCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.35
HTT P42858 1/20 0.35
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6548041 0.99 PLAU (0.34) PLAUHTTMAPTHPGDMAPK1
SCHEMBL6548456 0.97 PLAU (0.35) PLAUHTT
Hydrochloric Acid SCHEMBL6548709 0.96 PLAU (0.34) PLAUHTT
SCHEMBL6547818 0.96 PLAU (0.34) PLAUHTT
SCHEMBL6548732 0.96 PLAU (0.34) PLAUHTT
Hydrochloric Acid SCHEMBL6550066 0.94 PLAU (0.33) PLAUHTT
Hydrochloric Acid SCHEMBL6547483 0.94 PLAU (0.33) PLAUHTT
SCHEMBL8408794 0.92 HTT (0.39) PLAUHTTMAPTHPGDMAPK1
Hydrochloric Acid SCHEMBL6547824 0.91 PLAU (0.35) PLAUHTT
Hydrochloric Acid SCHEMBL6547375 0.90 KDM4E (0.35) HTTMAPTHPGDMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP claimed