Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117573 | 0.85 | GLA (0.32) | GLA | |
| SCHEMBL1058967 | 0.85 | — | — | |
| SCHEMBL18779 | 0.85 | — | — | |
| SCHEMBL30271302 | 0.82 | — | — | |
| Hydrogen Sulfide SCHEMBL15467095 | 0.82 | — | — | |
| Nitrous Acid SCHEMBL28305840 | 0.78 | CA1 (0.33) | CA1 | |
| Iodobenzene SCHEMBL28195013 | 0.77 | NOTUM (0.39) | GLANOTUMKMT2ACA12CA1 | |
| Acetonitrile SCHEMBL2051486 | 0.76 | — | — | |
| SCHEMBL23430212 | 0.73 | BRD4 (0.39) | LMNAKMT2A | |
| SCHEMBL11114696 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162962-B1 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2004-12-01 | — | — | EP | claimed |