SCHEMBL6551251

SCHEMBL6551251

CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CNC(=O)C(CP(=O)(O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 16/20 1.00
FNTB P49356 13/20 1.00
PGGT1B P53609 4/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551264 1.00 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL1803900 1.00 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL1803907 1.00 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL8967585 0.90 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL8967594 0.90 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL8079120 0.84 FNTA (0.71) FNTAFNTBPGGT1B
SCHEMBL6551715 0.82 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL6551717 0.82 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL8967850 0.82 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL8967871 0.82 FNTA (1.00) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0862575-B1 NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS BALDACCI LAB SPA (IT) 2004-02-11 EP claimed
US-6242433-B1 HAVING ANTIPROLIFERATIVE ACTIVITY IN EUKARYOTIC CELLS WITH RESPECT TO THE INHIBITION OF PROTEIN GERANYGERANYLATION. LABORATORI BALDACCI SPA (IT) 2001-06-05 US claimed
EP-0862575-B1 NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS BALDACCI LAB SPA (IT) 2004-02-11 EP disclosed
US-6242433-B1 HAVING ANTIPROLIFERATIVE ACTIVITY IN EUKARYOTIC CELLS WITH RESPECT TO THE INHIBITION OF PROTEIN GERANYGERANYLATION. LABORATORI BALDACCI SPA (IT) 2001-06-05 US disclosed
EP-0862575-A1 NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS LABORATORI BALDACCI Spa (IT) 1998-09-09 EP disclosed