Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 9/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | TXN | P10599 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6551875 | 1.00 | PNP (0.49) | PNPFGFR1FGFR2TXNKDM4E | |
| SCHEMBL7032324 | 1.00 | PNP (0.49) | PNPFGFR1FGFR2TXNKDM4E | |
| SCHEMBL8071957 | 1.00 | PNP (0.49) | PNPFGFR1FGFR2TXNKDM4E | |
| SCHEMBL8785781 | 0.97 | PNP (0.49) | PNPFGFR1FGFR2TXNKDM4E | |
| SCHEMBL313768 | 0.77 | PNP (0.47) | PNPKDM4EMEN1MAPTKMT2A | |
| SCHEMBL8789697 | 0.77 | PNP (0.47) | PNPKDM4EMEN1MAPTKMT2A | |
| SCHEMBL10661597 | 0.77 | PNP (0.47) | PNPKDM4EMEN1MAPTKMT2A | |
| SCHEMBL2185989 | 0.77 | PNP (0.47) | PNPKDM4EMEN1MAPTKMT2A | |
| SCHEMBL1682962 | 0.77 | PNP (0.47) | PNPKDM4EMEN1MAPTKMT2A | |
| SCHEMBL7948406 | 0.77 | PNP (0.47) | PNPKDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788507-B1 | L-PYRANOSYL NUCLEOSIDES | GENENCOR INT (US) | 2004-12-15 | — | — | EP | claimed |
| US-5885972-A | ANTICARCINOGENIC AGENT | GENENCOR INTERNATIONAL, INC. (US) | 1999-03-23 | — | — | US | claimed |
| EP-0788507-B1 | L-PYRANOSYL NUCLEOSIDES | GENENCOR INT (US) | 2004-12-15 | — | — | EP | disclosed |
| US-5885972-A | ANTICARCINOGENIC AGENT | GENENCOR INTERNATIONAL, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0788507-A1 | L-PYRANOSYL NUCLEOSIDES | GENENCOR INTERNATIONAL, INC. (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996012728-A1 | L-PYRANOSYL NUCLEOSIDES | GENENCOR INTERNATIONAL, INC. (US) | 1996-05-02 | — | — | WO | disclosed |