Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2391876 | 0.91 | HSD17B2 (0.57) | TSHRCYP3A4HSD17B2BLMNPSR1 | |
| SCHEMBL3835048 | 0.88 | PPARG (0.53) | NFKB1GAAACHEMEN1ALDH1A1 | |
| SCHEMBL30375902 | 0.88 | TSHR (0.60) | TSHRCYP3A4BLMNPSR1NFKB1 | |
| SCHEMBL17179845 | 0.87 | HSD17B2 (0.54) | TSHRCYP3A4HSD17B2BLMNPSR1 | |
| SCHEMBL3182348 | 0.84 | TSHR (0.65) | TSHRCYP3A4BLMNPSR1NFKB1 | |
| SCHEMBL490843 | 0.82 | HSD17B2 (0.57) | TSHRCYP3A4HSD17B2BLMNPSR1 | |
| SCHEMBL16231326 | 0.81 | HSD17B2 (0.56) | TSHRCYP3A4HSD17B2BLMNPSR1 | |
| Alcohol SCHEMBL17179872 | 0.79 | TSHR (0.63) | TSHRCYP3A4BLMNPSR1NFKB1 | |
| SCHEMBL298386 | 0.79 | TSHR (0.67) | TSHRCYP3A4BLMNPSR1NFKB1 | |
| SCHEMBL11582477 | 0.79 | CA12 (0.52) | GAAACHEMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904396-B1 | PRODUCTION OF VANILLIN | PLANT BIOSCIENCE LTD (GB) | 2004-02-18 | — | — | EP | disclosed |
| US-6664088-B2 | Reacting trans-ferulic acid and coenzyme a (CoASH) under trans-ferulate:CoASH ligase enzyme activity, trans-feruloyl SCoA hydratase activity, and 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl SCoA cleavage activity; Pseudomonas enzymes | PLANT BIOSCIENCE LIMITED (GB) | 2003-12-16 | — | — | US | disclosed |
| US-20030167511-A1 | Production of p-hydroxybenzoic acid | PLANT BIOSCIENCE LIMITED (GB) | 2003-09-04 | — | — | US | disclosed |
| US-6323011-B1 | PROVIDING TRANS-FERULIC ACID OR ITS SALT; COMBINING WITH ENZYME ACTIVITY I, ENZYME ACTIVITY II, AND ENZYME ACTIVITY III, WHEREIN ENZYME ACTIVITY I, ENZYME ACTIVITY II, AND ENZYME ACTIVITY III CATALYZE THE PRODUCTION OF VANILLIN | INSTITUTE OF FOOD RESEARCH (GB) | 2001-11-27 | — | — | US | disclosed |
| US-20010014467-A1 | Production of vanillin | NARBAD ARJAN (GB) | 2001-08-16 | — | — | US | disclosed |
| EP-0904396-A2 | PRODUCTION OF VANILLIN | INSTITUTE OF FOOD RESEARCH (GB) | 1999-03-31 | — | — | EP | disclosed |
| WO-1997035999-A2 | PRODUCTION OF VANILLIN | INSTITUTE OF FOOD RESEARCH (GB) | 1997-10-02 | — | — | WO | disclosed |