Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27812039 | 0.79 | ESR1 (0.53) | MEN1KMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL27791053 | 0.79 | ESR1 (0.53) | MEN1KMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL27793924 | 0.79 | ESR1 (0.53) | MEN1KMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL27812038 | 0.79 | ESR1 (0.53) | MEN1KMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL27791055 | 0.79 | ESR1 (0.53) | MEN1KMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL27862084 | 0.79 | ESR1 (0.53) | MEN1KMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL27793591 | 0.79 | ESR1 (0.53) | MEN1KMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL298017 | 0.78 | ESR1 (0.37) | L3MBTL1ESR1ESR2KIF11 | |
| SCHEMBL27796100 | 0.73 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL15043686 | 0.72 | POLB (0.50) | SMN1; SMN2POLBL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485106-A2 | PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2004-12-15 | — | — | EP | claimed |
| WO-2003070179-A2 | PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-08-28 | — | — | WO | claimed |
| EP-1485106-A2 | PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003070179-A2 | PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-08-28 | — | — | WO | disclosed |