O-Xylene

O-Xylene

SCHEMBL6552476

Cc1ccccc1C.Cc1ccccc1CO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
ACHE P22303 1/20 0.53
TAAR1 Q96RJ0 1/20 0.50
PDCD1 Q15116 1/20 0.48
CD274 Q9NZQ7 1/20 0.48
APOBEC3G Q9HC16 1/20 0.46
HPGD P15428 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CTBP2 P56545 1/20 0.42
CHRM2 P08172 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP2A13 Q16696 1/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2A6 P11509 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3338 0.97
SCHEMBL29928074 0.97
Ammonia Solution, Strong SCHEMBL9578178 0.95 TAAR1 (0.50) TSHRACHETAAR1PDCD1CD274
Bromide SCHEMBL27700459 0.95 TAAR1 (0.50) TSHRACHETAAR1PDCD1CD274
Water SCHEMBL809420 0.95 TAAR1 (0.50) TSHRACHETAAR1PDCD1CD274
Ammonia Solution, Strong SCHEMBL7943190 0.92 TAAR1 (0.48) TSHRACHETAAR1PDCD1CD274
Methane SCHEMBL17220519 0.92 TAAR1 (0.48) TSHRACHETAAR1PDCD1CD274
Alcohol SCHEMBL3319612 0.90 TAAR1 (0.46) TSHRACHETAAR1PDCD1CD274
Methylene Chloride SCHEMBL29159187 0.90 TAAR1 (0.46) TSHRACHETAAR1PDCD1CD274
Chloroform SCHEMBL11407017 0.88 TAAR1 (0.45) TSHRACHETAAR1PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114524715-B Directional hydrogenation method for carbonyl compound 河北工业大学 2023-10-13 CN disclosed
CN-114524715-A Method for directionally hydrogenating carbonyl compound 河北工业大学 2022-05-24 CN disclosed
EP-1485470-A2 USE OF XYLENE MONOOXYGENASE FOR THE OXIDATION OF SUBSTITUTED MONOCYCLIC AROMATIC COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-12-15 EP disclosed
WO-2003014368-A2 USE OF XYLENE MONOOXYGENASE FOR THE OXIDATION OF SUBSTITUTED MONOCYCLIC AROMATIC COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-20 WO disclosed