SCHEMBL6552532

SCHEMBL6552532

Cc1cc(C(=O)O)cc(S(=O)(=O)O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.73
FYN P06241 1/20 0.73
TPMT P51580 1/20 0.61
HCAR1 Q9BXC0 1/20 0.53
CYP1A2 P05177 1/20 0.44
HCAR2 Q8TDS4 1/20 0.42
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
ALDH1A1 P00352 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CNR2 P34972 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10868520 0.98 LCK (0.70) LCKFYNTPMTHCAR1CYP1A2
SCHEMBL698240 0.85 LCK (0.91) LCKFYNTPMTCYP1A2ALDH1A1
SCHEMBL63440 0.85 LCK (1.00) LCKFYNTPMTCYP1A2ALDH1A1
SCHEMBL31031074 0.85 LCK (1.00) LCKFYNTPMTCYP1A2ALDH1A1
SCHEMBL20790528 0.84 TPMT (0.61) LCKFYNTPMTHCAR1CYP1A2
SCHEMBL30525077 0.84 TPMT (0.61) LCKFYNTPMTHCAR1CYP1A2
SCHEMBL1723587 0.83 LCK (0.87) LCKFYNTPMTHCAR1CYP1A2
SCHEMBL433794 0.83 LCK (0.95) LCKFYNTPMTCYP1A2ALDH1A1
SCHEMBL6292108 0.83 LCK (0.95) LCKFYNTPMTCYP1A2ALDH1A1
Hydrochloric Acid SCHEMBL9830310 0.83 LCK (0.86) LCKFYNTPMTCYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7533978-B2 Color composition and inkjet recording method FUJIFILM CORPORATION (JP) 2009-05-19 US disclosed
EP-1485470-A2 USE OF XYLENE MONOOXYGENASE FOR THE OXIDATION OF SUBSTITUTED MONOCYCLIC AROMATIC COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-12-15 EP disclosed
US-20030073206-A1 Use of xylene monooxygenase for the oxidation of substituted monocyclic aromatic compounds E. I. DU PONT DE NEMOURS AND COMPANY 2003-04-17 US disclosed
WO-2003014368-A2 USE OF XYLENE MONOOXYGENASE FOR THE OXIDATION OF SUBSTITUTED MONOCYCLIC AROMATIC COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-20 WO disclosed