Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | PRKCA | P17252 | 4/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.56 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.56 |
| ▸ | DGKA | P23743 | 2/20 | 0.53 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695575 | 1.00 | CYP3A4 (0.66) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL6552520 | 1.00 | CYP3A4 (0.66) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL29221993 | 1.00 | CYP3A4 (0.66) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL29148386 | 0.98 | CYP3A4 (0.69) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL25924140 | 0.98 | CYP3A4 (0.64) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL16826386 | 0.97 | CYP3A4 (0.66) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL16013015 | 0.97 | CYP3A4 (0.66) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL26211677 | 0.95 | CYP3A4 (0.64) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL16882778 | 0.94 | CYP3A4 (0.77) | CYP3A4TSHRATMTDP1LMNA | |
| SCHEMBL22029525 | 0.93 | CYP3A4 (0.74) | CYP3A4TSHRATMTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097930-B1 | Method for producing macrocyclic lactone | KAO CORP (JP) | 2004-02-11 | — | — | EP | disclosed |
| US-6617304-B1 | Subjecting a hydroxycarboxylic acid ester to intramolecular esterification reaction,which may be obtained by partially reducing a dibasic acid in the presence of an alcohol | KAO CORPORATION (JP) | 2003-09-09 | — | — | US | disclosed |
| EP-1097930-A1 | Method for producing macrocyclic lactone | Kao Corporation (JP) | 2001-05-09 | — | — | EP | disclosed |