Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 10/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA4 | P22748 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540585 | 1.00 | ADRB3 (0.47) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6540723 | 0.95 | ADRB3 (0.53) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6540720 | 0.95 | ADRB3 (0.53) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6540725 | 0.95 | ADRB3 (0.53) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6541043 | 0.94 | ADRB3 (0.44) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6541054 | 0.94 | ADRB3 (0.44) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6539972 | 0.93 | CA12 (0.48) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6539979 | 0.93 | CA12 (0.48) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6539982 | 0.93 | CA12 (0.48) | ADRB3ADRB1ADRB2CYP2D6ADRA1D | |
| SCHEMBL6540102 | 0.91 | ADRB3 (0.52) | ADRB3ADRB1ADRB2CYP2D6ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |