Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6553027 | 0.96 | KCNA5 (0.49) | F2MCHR1KCNA5HRH3DRD3 | |
| SCHEMBL6553561 | 0.83 | CD274 (0.49) | MCHR1KCNA5HRH3DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL6554468 | 0.82 | MCHR1 (0.50) | MCHR1HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL7140961 | 0.73 | MCHR1 (0.73) | MCHR1HRH3HTT | |
| Acetic Acid SCHEMBL7451815 | 0.73 | F2 (0.68) | F2F10PRSS2 | |
| SCHEMBL7606279 | 0.72 | F2 (0.69) | F2F10PRSS2 | |
| Acetic Acid SCHEMBL8366230 | 0.72 | KCNA5 (0.67) | KCNA5DRD3DRD2MEN1KMT2A | |
| SCHEMBL6553403 | 0.71 | MAOB (0.52) | F2MAOAMAOBMEN1KMT2A | |
| Acetic Acid SCHEMBL7443924 | 0.71 | F2 (0.66) | F2F10PRSS2 | |
| SCHEMBL30858768 | 0.70 | MAOB (0.48) | F2MAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883405-B1 | AMIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2004-02-25 | — | — | EP | claimed |