⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL27702286 | 0.91 | — | — | |
| SCHEMBL6863659 | 0.82 | — | — | |
| SCHEMBL7160125 | 0.82 | — | — | |
| SCHEMBL2718 | 0.71 | — | — | |
| Ethane SCHEMBL10823097 | 0.71 | — | — | |
| Ethane SCHEMBL905431 | 0.71 | — | — | |
| SCHEMBL6191 | 0.71 | — | — | |
| SCHEMBL27498205 | 0.71 | — | — | |
| SCHEMBL8012781 | 0.71 | — | — | |
| Ethane SCHEMBL10894685 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171416-B1 | 3-BICYCLOARYL-2-AMINOMETHYL BICYCLOALKANES AS SEROTONINE REUPTAKE INHIBITORS | LILLY CO ELI (GB) | 2004-02-18 | — | — | EP | disclosed |
| US-6384281-B1 | USED IN TREATING NERVOUS SYSTEM DISORDERS E.G DEPRESSION, ALCOHOLISM, PAIN, HYPERTENSION, ALZHEIMER'S, MEMORY LOSS, ATTENTION-DEFICIT/OBSESSIVE COMPULSIVE/GASTRIC/CARDIOVASCULAR DISORDERS, PARKINSON'S, ANXIETY, CHRONIC FATIGUE SYNDROME, | ELI LILLY AND COMPANY | 2002-05-07 | — | — | US | disclosed |
| EP-1171416-A1 | 3-BICYCLOARYL-2-AMINOMETHYL BICYCLOALKANES AS SEROTONINE REUPTAKE INHIBITORS | ELI LILLY AND COMPANY LIMITED (GB) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000061539-A1 | 3-BICYCLOARYL-2-AMINOMETHYL BICYCLOALKANES AS SEROTONINE REUPTAKE INHIBITORS | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-19 | — | — | WO | disclosed |