Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187930 | 0.76 | MAPT (0.40) | CYP3A4ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL20187928 | 0.76 | MAPT (0.40) | CYP3A4ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL20188285 | 0.76 | MAPT (0.40) | CYP3A4ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL25406721 | 0.76 | CYP3A4 (0.37) | CYP3A4ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL22644821 | 0.73 | MAPT (0.38) | CYP3A4ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL8026282 | 0.70 | CYP3A4 (0.42) | CYP3A4ALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL6233396 | 0.69 | KDM4E (0.36) | ALDH1A1POLBKDM4E | |
| SCHEMBL8774567 | 0.68 | CYP3A4 (0.37) | CYP3A4ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL6233301 | 0.67 | GAA (0.46) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL4543295 | 0.67 | CYP3A4 (0.35) | CYP3A4MAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070706-B1 | Process for the preparation of 1-substituted 5-hydroxy-imidazolin-2,4-diones and 1-substituted 5-alkoxy-imidazolin-2,4-diones | BAYER CHEMICALS AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-6365752-B1 | REACTING GLYOXYLIC ACID AND AN N-SUBSTITUTED UREA IN AQUEOUS SOLUTION AND IN THE PRESENCE OF AN ACID CATALYST; EFFICIENCY; PURITY; NONTOXIC CHEMICAL INTERMEDIATES FOR DRUGS; INSECTICIDES; AMINO ACIDS AND TEXTILE ASSISTANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |
| EP-1070706-A1 | Process for the preparation of 1-substituted 5-hydroxy-imidazolin-2,4-diones and 1-substituted 5-alkoxy-imidazolin-2,4-diones | BAYER AG (DE) | 2001-01-24 | — | — | EP | disclosed |