Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 13/20 | 0.36 |
| ▸ | GBA1 | P04062 | 8/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28011845 | 0.79 | TAAR1 (0.52) | TAAR1GNAO1GNAI3GNAI1GBA1 | |
| SCHEMBL7022097 | 0.79 | TAAR1 (0.52) | TAAR1GNAO1GNAI3GNAI1GBA1 | |
| SCHEMBL6439309 | 0.79 | TAAR1 (0.52) | TAAR1GNAO1GNAI3GNAI1GBA1 | |
| SCHEMBL11015512 | 0.79 | TAAR1 (0.52) | TAAR1GNAO1GNAI3GNAI1GBA1 | |
| SCHEMBL6566400 | 0.79 | TAAR1 (0.52) | TAAR1GNAO1GNAI3GNAI1GBA1 | |
| SCHEMBL27832364 | 0.79 | TAAR1 (0.52) | TAAR1GNAO1GNAI3GNAI1GBA1 | |
| SCHEMBL27911335 | 0.79 | TAAR1 (0.54) | TAAR1GNAO1GNAI3GNAI1S1PR4 | |
| Iodide SCHEMBL28818073 | 0.78 | TAAR1 (0.51) | TAAR1GNAO1GNAI3GNAI1GBA1 | |
| SCHEMBL4446755 | 0.77 | TAAR1 (0.53) | TAAR1GNAO1GNAI3GNAI1GBA1 | |
| SCHEMBL250854 | 0.77 | TAAR1 (0.53) | TAAR1GNAO1GNAI3GNAI1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929536-B1 | PIPERAZINE BASED CYTOFECTINS | VICAL INC (US) | 2004-12-22 | — | — | EP | disclosed |