Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540905 | 0.89 | ADRB3 (0.41) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6540908 | 0.89 | ADRB3 (0.41) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6552762 | 0.86 | ADRB3 (0.39) | ADRB3ADRB1ADRB2ALDH1A1 | |
| SCHEMBL6541467 | 0.85 | NAMPT (0.41) | ADRB3ADRB1ADRB2NAMPT | |
| SCHEMBL6541472 | 0.85 | NAMPT (0.41) | ADRB3ADRB1ADRB2NAMPT | |
| SCHEMBL6552792 | 0.85 | ADRB3 (0.40) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6541210 | 0.82 | BACE1 (0.39) | ADRB3ADRB1ADRB2CA1CA2 | |
| SCHEMBL6541213 | 0.82 | BACE1 (0.39) | ADRB3ADRB1ADRB2CA1CA2 | |
| SCHEMBL6800050 | 0.82 | ADRB3 (0.39) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6800053 | 0.82 | ADRB3 (0.39) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |