Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823984 | 1.00 | — | — | |
| SCHEMBL7736881 | 1.00 | TSHR (0.52) | TSHRABCC4MAPTALDH1A1TRPA1 | |
| SCHEMBL5702283 | 1.00 | TSHR (0.52) | TSHRABCC4MAPTALDH1A1TRPA1 | |
| SCHEMBL1933123 | 1.00 | TSHR (0.52) | TSHRABCC4MAPTALDH1A1TRPA1 | |
| SCHEMBL10672762 | 0.87 | — | — | |
| SCHEMBL2846645 | 0.83 | TSHR (0.69) | TSHRABCC4MAPTALDH1A1TRPA1 | |
| SCHEMBL18187344 | 0.83 | TSHR (0.69) | TSHRABCC4MAPTALDH1A1TRPA1 | |
| SCHEMBL477953 | 0.83 | TSHR (0.69) | TSHRABCC4MAPTALDH1A1TRPA1 | |
| SCHEMBL18186951 | 0.83 | TSHR (0.69) | TSHRABCC4MAPTALDH1A1TRPA1 | |
| SCHEMBL18187342 | 0.83 | TSHR (0.69) | TSHRABCC4MAPTALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000950-B1 | Novel indanylidene compounds | HOFFMANN LA ROCHE (CH) | 2004-02-25 | — | — | EP | disclosed |