Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556806 | 0.81 | KMT2A (0.58) | KMT2AMEN1GAAALDH1A1CNR1 | |
| SCHEMBL7157119 | 0.76 | GAA (0.52) | KMT2AMEN1GAAALDH1A1CNR1 | |
| SCHEMBL6554732 | 0.76 | MEN1 (0.53) | KMT2AMEN1GAAALDH1A1CNR1 | |
| SCHEMBL6554726 | 0.76 | MEN1 (0.53) | KMT2AMEN1GAAALDH1A1CNR1 | |
| SCHEMBL5642269 | 0.75 | KMT2A (0.52) | KMT2AMEN1GAAALDH1A1CNR1 | |
| SCHEMBL6555985 | 0.74 | KMT2A (0.55) | KMT2AMEN1GAAALDH1A1CNR1 | |
| SCHEMBL7156842 | 0.74 | KMT2A (0.55) | KMT2AMEN1GAAALDH1A1CNR1 | |
| SCHEMBL6554738 | 0.74 | KMT2A (0.51) | KMT2AMEN1GAAALDH1A1CNR1 | |
| SCHEMBL6555996 | 0.73 | KMT2A (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6556893 | 0.72 | GAA (0.52) | KMT2AMEN1GAAALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135368-B1 | ALPHA-SULFIN- AND ALPHA-SULFON-AMINO ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-25 | — | — | EP | disclosed |
| US-6538016-B2 | For controlling and preventing an infestation of crop plants by phytopathogenic microorganisms, preferably fungi | SYNGENTA PARTICIPATIONS AG (CH) | 2003-03-25 | — | — | US | disclosed |
| EP-1135368-A2 | ALPHA-SULFIN- AND ALPHA-SULFON-AMINO ACID AMIDES | Syngenta Participations AG (CH) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000032568-A2 | $G(A)-SULFIN- AND $G(A)-SULFONAMINO ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-06-08 | — | — | WO | disclosed |