Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7480501 | 0.99 | TACR1 (0.74) | TACR1CYP2D6 | |
| SCHEMBL6556858 | 0.92 | TACR1 (0.76) | TACR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7474243 | 0.91 | TACR1 (0.74) | TACR1CYP2D6 | |
| SCHEMBL6554450 | 0.91 | TACR1 (0.74) | TACR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7475900 | 0.90 | TACR1 (0.73) | TACR1CYP2D6 | |
| SCHEMBL6554854 | 0.90 | TACR1 (0.72) | TACR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7477227 | 0.89 | TACR1 (0.71) | TACR1CYP2D6 | |
| SCHEMBL6554849 | 0.88 | TACR1 (0.69) | TACR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7477221 | 0.87 | TACR1 (0.68) | TACR1CYP2D6 | |
| SCHEMBL22272194 | 0.87 | TACR1 (0.77) | TACR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721778-B1 | NK-1 receptor antagonists for the treatment of neuronal injury and stroke | PFIZER (US) | 2004-03-03 | — | — | EP | claimed |
| JP-2003523941-A | — | — | 2003-08-12 | — | — | JP | claimed |
| EP-1209157-A1 | Heteroarylamino and heteroarylsulfonamido substituted 3-benzylaminomethyl piperidines and related compounds | PFIZER INC. (US) | 2002-05-29 | — | — | EP | claimed |
| EP-1178784-A1 | NEW PHARMACEUTICAL COMBINATIONS FOR NOS INHIBITORS | Pfizer Products Inc. (US) | 2002-02-13 | — | — | EP | claimed |
| US-6194436-B1 | THERAPY FOR LUNG CANCER | PFIZER INC. | 2001-02-27 | — | — | US | claimed |
| WO-2000071107-A2 | NEW PHARMACEUTICAL COMBINATIONS FOR NOS INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-11-30 | — | — | WO | claimed |
| EP-0854720-B1 | NK-1 RECEPTOR ANTAGONISTS FOR PREVENTION OF NEUROGENIC INFLAMMATION IN GENE THERAPY | PFIZER (US) | 1999-08-04 | — | — | EP | claimed |
| EP-0790825-A1 | NK-1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF EYE DISORDERS | PFIZER INC. (US) | 1997-08-27 | — | — | EP | claimed |
| EP-0773026-A2 | NK-1 receptor antagonists for the treatment of cancer | PFIZER INC. (US) | 1997-05-14 | — | — | EP | claimed |
| US-5576317-A | NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis | PFIZER INC. (US) | 1996-11-19 | — | — | US | claimed |
| EP-0721778-A2 | NK-1 receptor antagonists for the treatment of neuronal injury and stroke | PFIZER INC. (US) | 1996-07-17 | — | — | EP | claimed |
| EP-0715855-A2 | NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis | PFIZER INC. (US) | 1996-06-12 | — | — | EP | claimed |
| WO-1996014845-A1 | NK-1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF EYE DISORDERS | PFIZER INC. (US) | 1996-05-23 | — | — | WO | claimed |
| EP-0659409-A2 | Substance 1 antagonists for the inhibition of angiogenesis | PFIZER INC. (US) | 1995-06-28 | — | — | EP | claimed |
| EP-0655246-A1 | Substance P antagonists for the treatment of disorders caused by helicobacter pylori or other spiral urease-positive gram-negative bacteria | PFIZER INC. (US) | 1995-05-31 | — | — | EP | claimed |
| EP-0653208-A2 | Pharmaceutical agents for treatment or prevention of sunburn | PFIZER INC. (US) | 1995-05-17 | — | — | EP | claimed |
| WO-1995007908-A1 | HETEROARYLAMINO AND HETEROARYLSULFONAMIDO SUBSTITUTED 3-BENZYLAMINOMETHYL PIPERIDINES AND RELATED COMPOUNDS | PFIZER INC. (US) | 1995-03-23 | — | — | WO | claimed |
| EP-0721778-B1 | NK-1 receptor antagonists for the treatment of neuronal injury and stroke | PFIZER (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-0653208-A2 | Pharmaceutical agents for treatment or prevention of sunburn | PFIZER INC. (US) | 1995-05-17 | — | — | EP | disclosed |
| WO-1995007908-A1 | HETEROARYLAMINO AND HETEROARYLSULFONAMIDO SUBSTITUTED 3-BENZYLAMINOMETHYL PIPERIDINES AND RELATED COMPOUNDS | PFIZER INC. (US) | 1995-03-23 | — | — | WO | disclosed |