SCHEMBL6555318

SCHEMBL6555318

[CH2]C(=O)Oc1c(F)cccc1C=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.50
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.37
SRC P12931 2/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
BLM P54132 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TLR2 O60603 1/20 0.35
TLR1 Q15399 1/20 0.35
TLR6 Q9Y2C9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6555324 0.83 ERN1 (0.55) ERN1CA1CA2PTGDR2SRC
SCHEMBL4647881 0.82 ERN1 (0.46) ERN1CA1CA2PTGDR2SRC
SCHEMBL4645683 0.81 CA1 (0.61) ERN1CA1CA2PTGDR2SRC
SCHEMBL4647875 0.80 ERN1 (0.47) ERN1CA1CA2PTGDR2SRC
SCHEMBL4641991 0.80 ERN1 (0.47) ERN1CA1CA2PTGDR2SRC
SCHEMBL4646426 0.80 ERN1 (0.44) ERN1CA1CA2PTGDR2SRC
SCHEMBL4641803 0.79 ERN1 (0.46) ERN1CA1CA2PTGDR2SRC
SCHEMBL1665123 0.78 TP53 (0.51) ERN1KMT2AMEN1SMN1; SMN2
SCHEMBL4644381 0.78 ERN1 (0.45) ERN1CA1CA2PTGDR2SRC
SCHEMBL4646424 0.78 ERN1 (0.45) ERN1CA1CA2PTGDR2SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed