Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.36 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL963513 | 0.83 | TSHR (0.49) | TSHRHPGDUSP2CYP3A4MAPT | |
| SCHEMBL214500 | 0.83 | TSHR (0.49) | TSHRHPGDUSP2CYP3A4MAPT | |
| SCHEMBL30841757 | 0.75 | TSHR (0.41) | TSHRHPGDALDH1A1 | |
| SCHEMBL29842337 | 0.72 | TSHR (0.43) | TSHRDGKAHPGDUSP2CYP3A4 | |
| SCHEMBL16937425 | 0.71 | TSHR (0.69) | TSHRFAAHHPGDCYP3A4LMNA | |
| SCHEMBL30512961 | 0.71 | TSHR (0.51) | TSHRHPGDCYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL6518053 | 0.71 | TSHR (0.47) | TSHRHPGDUSP2CYP3A4MAPT | |
| SCHEMBL2504035 | 0.71 | GSTP1 (0.30) | HPGDUSP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL30475044 | 0.71 | TSHR (0.66) | TSHRHPGDCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9242066 | 0.71 | TSHR (0.58) | TSHRFAAHHPGDCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124893-B1 | POLYISOCYANATE POLYADDITION PRODUCTS | BASF AG (DE) | 2004-12-22 | — | — | EP | disclosed |
| EP-1124893-A1 | POLYISOCYANATE POLYADDITION PRODUCTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-22 | — | — | EP | disclosed |
| WO-2001000721-A1 | POLYISOCYANATE POLYADDITION PRODUCTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |