⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29199845 | 0.98 | — | — | |
| Bromide SCHEMBL2260939 | 0.98 | — | — | |
| Fluoride SCHEMBL28230601 | 0.96 | — | — | |
| SCHEMBL1041558 | 0.93 | — | — | |
| SCHEMBL4458780 | 0.71 | — | — | |
| SCHEMBL11553854 | 0.69 | — | — | |
| Bromide SCHEMBL28720815 | 0.68 | — | — | |
| SCHEMBL5795034 | 0.67 | — | — | |
| SCHEMBL27703879 | 0.64 | — | — | |
| SCHEMBL2260942 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117919397-B | Pneumococcal conjugate combined vaccine and preparation method thereof | 北京智飞绿竹生物制药有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-118021947-A | Neisseria meningitidis compositions and methods of use thereof | 辉瑞大药厂 | 2024-05-14 | — | — | CN | claimed |
| CN-117919397-A | Pneumococcal conjugate combined vaccine and preparation method thereof | 北京智飞绿竹生物制药有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-110234658-B | Neisseria meningitidis compositions and methods of use thereof | 辉瑞大药厂 | 2024-03-12 | — | — | CN | claimed |
| CN-108144056-A | Polyvalent pneumococcal polysaccharide combination vaccine and preparation method thereof | 武汉博沃生物科技有限公司 | 2018-06-12 | — | — | CN | claimed |
| CN-108144052-A | Streptococcus pneumoniae polysaccharides-protein conjugate and its preparation method and purposes | 武汉博沃生物科技有限公司 | 2018-06-12 | — | — | CN | claimed |
| EP-1124576-B1 | METHOD FOR PREPARING SOLID PHASE CONJUGATE VACCINES | JACKSON H M FOUND MILITARY MED (US) | 2004-12-29 | — | — | EP | claimed |
| EP-0720485-B1 | METHOD OF ACTIVATING SOLUBLE CARBOHYDRATE USING NOVEL CYANYLATING REAGENTS FOR THE PRODUCTION OF IMMUNOGENIC CONSTRUCTS | JACKSON H M FOUND MILITARY MED (US) | 2003-11-19 | — | — | EP | claimed |
| EP-4746917-A1 | VACCINE | GlaxoSmithKline Biologicals SA (BE) | 2026-05-27 | — | — | EP | disclosed |
| CN-114010775-B | Group B streptococcus polysaccharide-protein conjugates, methods of making conjugates, immunogenic compositions comprising conjugates, and uses thereof | 辉瑞大药厂 | 2025-06-10 | — | — | CN | disclosed |
| WO-2025021704-A1 | VACCINE | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2025-01-30 | — | — | WO | disclosed |
| CN-114739928-B | Method, reagent and kit for determining content of reducing sugar in pneumococcal activated sugar based on MBTH method | 北京成大天和生物科技有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-118831156-A | Combined vaccine and preparation method and application thereof | 康希诺生物股份公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118027423-A | Preparation method of pneumococcal polysaccharide protein 1 conjugate and product thereof | 成都康华生物制品股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-109890415-B | Multivalent pneumococcal polysaccharide-protein conjugate composition | 圣诺菲·帕斯图尔公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115605222-A | Neisseria meningitidis compositions and methods thereof | 辉瑞公司（US） | 2023-01-13 | — | — | CN | disclosed |
| CN-111821432-B | Multivalent pneumococcal conjugate vaccine | 北京智飞绿竹生物制药有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114739928-A | Method, reagent and kit for determining content of reducing sugar in pneumococcal activated sugar based on MBTH (Methylmetryferyl-beta) method | 北京成大天和生物科技有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-110234658-A | Neisseria meningitidis compositions and methods of use thereof | 辉瑞大药厂 | 2019-09-13 | — | — | CN | disclosed |
| CN-108367063-A | Immunogenic compositions comprising conjugated capsular saccharide antigens, kits and uses thereof | 辉瑞公司 | 2018-08-03 | — | — | CN | disclosed |