Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804749 | 1.00 | MAPT (0.47) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL6556887 | 0.83 | MAPT (0.61) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL6556764 | 0.81 | MAPT (0.68) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL30054040 | 0.81 | MAPT (0.68) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL6556696 | 0.78 | MAPT (0.47) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL6556720 | 0.78 | MAPT (0.47) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL6556706 | 0.77 | MAPT (0.55) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL6556773 | 0.77 | MAPT (0.62) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL6556767 | 0.74 | MAPT (0.57) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL6556834 | 0.72 | MAPT (0.54) | MAPTL3MBTL1CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100483-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6166013-A | Glucocortiocoid-selective agents | ABBOTT LABORATORIES (US) | 2000-12-26 | — | — | US | disclosed |