Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972466 | 0.83 | KCNN4 (0.43) | CES1KCNN4HIF1ACYP2C19CYP1A2 | |
| SCHEMBL2729130 | 0.76 | CES1 (0.46) | CES1KCNN4HIF1ACYP2C19CYP1A2 | |
| SCHEMBL3363882 | 0.74 | CES1 (0.44) | CES1KCNN4HIF1ACYP2C19CYP1A2 | |
| SCHEMBL28753479 | 0.74 | CES1 (0.44) | CES1KCNN4HIF1ACYP2C19CYP1A2 | |
| SCHEMBL18901487 | 0.74 | CES1 (0.44) | CES1KCNN4HIF1ACYP2C19KMT2A | |
| SCHEMBL7924474 | 0.74 | CES1 (0.44) | CES1KCNN4HIF1ACYP2C19CYP1A2 | |
| SCHEMBL6387363 | 0.74 | CYP2C19 (0.53) | CES1KCNN4HIF1ACYP2C19CYP1A2 | |
| SCHEMBL13183609 | 0.73 | CES1 (0.43) | CES1KCNN4HIF1ACYP2C19CYP1A2 | |
| SCHEMBL6529359 | 0.73 | MAPT (0.48) | CES1KCNN4HIF1ACYP2C19CYP1A2 | |
| SCHEMBL4557331 | 0.73 | MAPT (0.44) | KCNN4HIF1ACYP2C19CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423691-A1 | FLUORESCENCE BASED OXYGEN SENSOR SYSTEMS | 3M Innovative Properties Company (US) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003019179-A1 | FLUORESCENCE BASED OXYGEN SENSOR SYSTEMS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-03-06 | — | — | WO | disclosed |