Styrene

Styrene

SCHEMBL6557207

C=C(C)C(=O)OCCCCCCCCCCCC.C=C(C)C(=O)OCCN(C)C.C=Cc1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
TDP1 Q9NUW8 2/20 0.44
POLB P06746 2/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
ALDH1A1 P00352 2/20 0.42
DNM1 Q05193 1/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
THRA P10827 4/20 0.39
THRB P10828 4/20 0.39
BCHE P06276 2/20 0.39
ACHE P22303 2/20 0.39
ESR1 P03372 1/20 0.39
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL10510802 1.00 TSHR (0.55) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL9643402 0.95 TSHR (0.47) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL10512167 0.95 TSHR (0.49) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL4205045 0.92 TSHR (0.65) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL1984291 0.92 TSHR (0.65) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL1978653 0.92 TSHR (0.65) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL6762849 0.92 TSHR (0.65) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL9305486 0.91 TSHR (0.63) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL26633376 0.91 TSHR (0.63) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL446411 0.91 CHRM1 (0.43) TSHRTDP1POLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1172421-B1 Water-based ink composition KAO CORP (JP) 2004-12-29 EP disclosed
US-6740690-B2 COMPRISING A POLYBASIC ACID, AN IONIC POLYMER AND A COLORING AGENT; FOR INK JET RECORDING KAO CORPORATION (JP) 2004-05-25 US disclosed
US-20020016385-A1 Comprising a polybasic acid, an ionic polymer and a coloring agent; for ink jet recording KAO CORPORATION (JP) 2002-02-07 US disclosed