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SCHEMBL6557672

SCHEMBL6557672

COC(=O)c1ccc(COC(=O)Nc2ccc(-c3ccccc3)n(CC(=O)NC(Cc3ccccc3)C(O[Si](C)(C)C(C)(C)C)C(F)(F)F)c2=O)cc1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 20/20 0.57
▸ CTRC Q99895 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6557635 0.94 ELANE (0.62) ELANECTRC
SCHEMBL6558314 0.94 ELANE (0.58) ELANECTRC
SCHEMBL7277022 0.89 ELANE (0.61) ELANECTRC
SCHEMBL6557690 0.88 ELANE (0.63) ELANECTRC
SCHEMBL6558243 0.85 ELANE (0.65) ELANECTRC
SCHEMBL7283926 0.85 ELANE (0.62) ELANECTRC
SCHEMBL7276661 0.85 ELANE (0.67) ELANECTRC
SCHEMBL6556339 0.83 ELANE (0.71) ELANECTRC
SCHEMBL6558271 0.82 ELANE (0.65) ELANECTRC
SCHEMBL7279603 0.81 ELANE (0.69) ELANECTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0826671-B1 HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME MITSUBISHI PHARMA CORP (JP) 2004-12-29 — — EP disclosed
EP-0826671-A1 HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME THE GREEN CROSS CORPORATION (JP) 1998-03-04 — — EP disclosed