Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392780 | 1.00 | CYP2C9 (0.49) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL30400657 | 1.00 | CYP2C9 (0.49) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8222402 | 0.99 | CYP2C9 (0.48) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8222400 | 0.99 | CYP2C9 (0.48) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8222398 | 0.99 | CYP2C9 (0.48) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL1754931 | 0.96 | CYP2C9 (0.46) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL28382459 | 0.92 | CYP2C9 (0.41) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL28366793 | 0.91 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL30309465 | 0.91 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL2396830 | 0.91 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8176033-A | — | — | None | — | — | JP | disclosed |
| EP-1223209-B1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INT LTD (CH) | 2004-03-03 | — | — | EP | disclosed |
| EP-1223209-A1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INTERNATIONAL LTD. (CH) | 2002-07-17 | — | — | EP | disclosed |
| US-6159393-A | Benzene derivatives and liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-12-12 | — | — | US | disclosed |
| EP-0775101-B1 | BENZENE DERIVATIVES AND LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2000-05-03 | — | — | EP | disclosed |
| EP-0775101-A1 | BENZENE DERIVATIVES AND LIQUID CRYSTAL MEDIUM | MERCK PATENT GmbH (DE) | 1997-05-28 | — | — | EP | disclosed |
| JP-H08176033-A | BENZENE DERIVATIVE | MERCK PATENT GMBH | 1996-07-09 | — | — | JP | disclosed |
| WO-1996005159-A1 | BENZENE DERIVATIVES AND LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |