SCHEMBL6558380

SCHEMBL6558380

COC(=O)CN(C1CCN(C(C)C(=O)N2CCCC2CN2CCCC2)C1=O)S(=O)(=O)c1ccc2cc(Cl)ccc2c1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6558379 1.00 F10 (0.60) F10
Formic Acid SCHEMBL5143053 0.97 F10 (0.57) F10
SCHEMBL5141849 0.94 F10 (0.68) F10
SCHEMBL5170695 0.94 F10 (0.68) F10
SCHEMBL5144951 0.93 F10 (0.57) F10
SCHEMBL6558364 0.93 F10 (0.57) F10
SCHEMBL5142789 0.91 F10 (0.70) F10
SCHEMBL6558344 0.91 F10 (0.70) F10
Formic Acid SCHEMBL6558361 0.91 F10 (0.65) F10
Formic Acid SCHEMBL5144946 0.91 F10 (0.65) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1395606-A1 PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF FACTOR XA GLAXO GROUP LIMITED (GB) 2004-03-10 EP disclosed
WO-2002100886-A1 PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF FACTOR XA GLAXO GROUP LIMITED (GB) 2002-12-19 WO disclosed