Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22278542 | 0.83 | SLC2A1 (0.53) | SLC2A1MAPTTSHRL3MBTL1LMNA | |
| SCHEMBL5011743 | 0.81 | SLC2A1 (0.59) | SLC2A1MAPTTSHRL3MBTL1MEN1 | |
| SCHEMBL4088685 | 0.80 | ACP3 (0.48) | TSHRMEN1KMT2AAOC3ALDH1A1 | |
| SCHEMBL7536675 | 0.79 | KMT2A (0.51) | SLC2A1MAPTTSHRL3MBTL1NPC1 | |
| SCHEMBL7110610 | 0.78 | SLC2A1 (0.61) | SLC2A1MAPTTSHRL3MBTL1MEN1 | |
| SCHEMBL61350 | 0.78 | SLC2A1 (0.61) | SLC2A1MAPTTSHRL3MBTL1MEN1 | |
| SCHEMBL61574 | 0.78 | SLC2A1 (0.71) | SLC2A1MAPTTSHRL3MBTL1MEN1 | |
| SCHEMBL9626237 | 0.78 | SLC2A1 (0.71) | SLC2A1MAPTTSHRL3MBTL1MEN1 | |
| Water SCHEMBL10498815 | 0.77 | SLC2A1 (0.59) | SLC2A1MAPTTSHRL3MBTL1MEN1 | |
| SCHEMBL11595893 | 0.76 | NSD2 (0.44) | SLC2A1MAPTTSHRL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100483-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2004-09-29 | — | — | EP | claimed |
| US-6166013-A | Glucocortiocoid-selective agents | ABBOTT LABORATORIES (US) | 2000-12-26 | — | — | US | disclosed |