SCHEMBL6558912

SCHEMBL6558912

C=CCOC(=O)CC(OC(=O)C(=C)C)C(=O)OCC=C

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 4/20 0.38
THRB P10828 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.30
PKM P14618 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10011565 0.85 TDP1 (0.41) TDP1TSHRNPSR1ALDH1A1CYP3A4
SCHEMBL10645448 0.83 TSHR (0.49) TDP1TSHRTHRBALDH1A1CYP3A4
SCHEMBL27835187 0.81 TDP1 (0.39) TDP1TSHRTHRBNPSR1ALDH1A1
SCHEMBL10012776 0.81 TDP1 (0.41) TDP1TSHRNPSR1ALDH1A1CYP3A4
SCHEMBL10011238 0.81 TSHR (0.44) TDP1TSHRNPSR1ALDH1A1CYP3A4
SCHEMBL13324132 0.79 TDP1 (0.38) TDP1TSHRNPSR1ALDH1A1CYP3A4
SCHEMBL16653509 0.79 MAPT (0.41) TDP1TSHRNPSR1ALDH1A1CYP3A4
SCHEMBL2385673 0.79 MGAM (0.42) TDP1TSHRTHRBALDH1A1CYP3A4
SCHEMBL8732985 0.78 TDP1 (0.44) TDP1TSHRNPSR1ALDH1A1CYP3A4
SCHEMBL14394060 0.78 TDP1 (0.36) TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1190866-B1 Photocrosslinkable latex protective overcoat for imaging elements EASTMAN KODAK CO (US) 2004-03-03 EP claimed
EP-1190866-A1 Photocrosslinkable latex protective overcoat for imaging elements EASTMAN KODAK COMPANY (US) 2002-03-27 EP claimed
US-6352805-B1 IMAGED ELEMENT HAVING PROTECTIVE OVERCOAT OF COMPOSITION COMPRISING REACTION PRODUCT OF WATER-DISPERSIBLE LATEX PARTICLES AND COPOLYMERIZABLE MULTIFUNCTIONAL MONOMER CROSSLINKED WITH ULTRAVIOLET LIGHT IN PRESENCE OF INITIATOR EASTMAN KODAK COMPANY 2002-03-05 US claimed
US-7300740-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2007-11-27 US disclosed
EP-1190866-B1 Photocrosslinkable latex protective overcoat for imaging elements EASTMAN KODAK CO (US) 2004-03-03 EP disclosed
US-6395459-B1 CURING; WATERPROOF PROTECTIVE COATING EASTMAN KODAK COMPANY 2002-05-28 US disclosed
EP-1193551-A2 A method of forming a protective overcoat for imaged elements and related articles EASTMAN KODAK COMPANY (US) 2002-04-03 EP disclosed
EP-1190866-A1 Photocrosslinkable latex protective overcoat for imaging elements EASTMAN KODAK COMPANY (US) 2002-03-27 EP disclosed
US-6352805-B1 IMAGED ELEMENT HAVING PROTECTIVE OVERCOAT OF COMPOSITION COMPRISING REACTION PRODUCT OF WATER-DISPERSIBLE LATEX PARTICLES AND COPOLYMERIZABLE MULTIFUNCTIONAL MONOMER CROSSLINKED WITH ULTRAVIOLET LIGHT IN PRESENCE OF INITIATOR EASTMAN KODAK COMPANY 2002-03-05 US disclosed
US-4107013-A INDUSTRIAL COATINGS; HIGH MOLECULAR WEIGHT POLYMER AND LOW MOLECULAR WEIGHT CROSSLINKING POLYMER SCM CORPORATION (US) 1978-08-15 US disclosed