Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | MAX | P61244 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 8/20 | 0.46 |
| ▸ | CTSL | P07711 | 5/20 | 0.46 |
| ▸ | CTSB | P07858 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559021 | 1.00 | ATM (0.49) | ATMMYCMAXHCAR3CTSL | |
| SCHEMBL6557796 | 0.92 | ATM (0.47) | ATMCTSLCTSBMAPTALDH1A1 | |
| SCHEMBL6557807 | 0.92 | ATM (0.47) | ATMCTSLCTSBMAPTALDH1A1 | |
| SCHEMBL6558080 | 0.85 | POLB (0.52) | ATMMYCMAXMAPTALDH1A1 | |
| SCHEMBL6558090 | 0.85 | POLB (0.52) | ATMMYCMAXMAPTALDH1A1 | |
| SCHEMBL7598666 | 0.83 | MEN1 (0.50) | HCAR3MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL6560303 | 0.82 | ATM (0.53) | ATMCTSLCTSBALDH1A1KDM4E | |
| SCHEMBL6559971 | 0.82 | ATM (0.53) | ATMCTSLCTSBMAPTALDH1A1 | |
| SCHEMBL6559979 | 0.82 | ATM (0.53) | ATMCTSLCTSBMAPTALDH1A1 | |
| SCHEMBL6560298 | 0.82 | ATM (0.53) | ATMCTSLCTSBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391454-A1 | Substituted benzamide compounds with antihypertensive activity | Mitsubishi Pharma Corporation (JP) | 2004-02-25 | — | — | EP | disclosed |
| EP-1195372-A1 | N-heterocyclic substituted benzamide derivatives with antihypertensive activity | Mitsubishi Pharma Corporation (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-6156766-A | Benzamide compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| US-5958944-A | TREATMENT OF CIRCULATORY DISEASES IN CORONARY, CEREBRAL, RENAL AND PERIPHERAL ARTERIES, AS A THERAPEUTIC AGENT FOR HYPERTENSION, ANGINA PECTORIS, AND RENAL AND PERIPHERAL CIRCULATION DISORDER, ANTIASTHMATIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0757038-A1 | BENZAMIDE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-05 | — | — | EP | disclosed |