SCHEMBL6559336

SCHEMBL6559336

CC(C(=O)N1CCCCCC1)N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5141766 1.00 F10 (1.00) F10
SCHEMBL6031005 1.00 F10 (1.00) F10
SCHEMBL5143506 1.00 F10 (1.00) F10
SCHEMBL5143314 1.00 F10 (1.00) F10
SCHEMBL5145041 1.00 F10 (1.00) F10
SCHEMBL5143445 1.00 F10 (1.00) F10
SCHEMBL5142895 1.00 F10 (1.00) F10
SCHEMBL5168985 1.00 F10 (1.00) F10
SCHEMBL5146145 0.99 F10 (1.00) F10
SCHEMBL5143258 0.99 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1395606-A1 PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF FACTOR XA GLAXO GROUP LIMITED (GB) 2004-03-10 EP disclosed
WO-2002100886-A1 PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF FACTOR XA GLAXO GROUP LIMITED (GB) 2002-12-19 WO disclosed