Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005495 | 1.00 | KCNH2 (0.49) | KCNH2DNM1EPHX2FAAHALDH1A1 | |
| SCHEMBL27772350 | 1.00 | KCNH2 (0.49) | KCNH2DNM1EPHX2FAAHALDH1A1 | |
| SCHEMBL6380984 | 1.00 | KCNH2 (0.49) | KCNH2DNM1EPHX2FAAHALDH1A1 | |
| SCHEMBL7458957 | 1.00 | KCNH2 (0.49) | KCNH2DNM1EPHX2FAAHALDH1A1 | |
| SCHEMBL10494813 | 1.00 | KCNH2 (0.49) | KCNH2DNM1EPHX2FAAHALDH1A1 | |
| SCHEMBL442769 | 1.00 | KCNH2 (0.49) | KCNH2DNM1EPHX2FAAHALDH1A1 | |
| SCHEMBL2549406 | 1.00 | KCNH2 (0.49) | KCNH2DNM1EPHX2FAAHALDH1A1 | |
| SCHEMBL9386106 | 1.00 | KCNH2 (0.49) | KCNH2DNM1EPHX2FAAHALDH1A1 | |
| SCHEMBL10494779 | 1.00 | KCNH2 (0.49) | KCNH2DNM1EPHX2FAAHALDH1A1 | |
| SCHEMBL28177024 | 1.00 | KCNH2 (0.49) | KCNH2DNM1EPHX2FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240156780-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AXIAL THERAPEUTICS, INC. (US) | 2024-05-16 | — | — | US | disclosed |
| US-11951094-B2 | TLR2 modulator compounds, pharmaceutical compositions and uses thereof | AXIAL THERAPEUTICS, INC. (US) | 2024-04-09 | — | — | US | disclosed |
| EP-4171547-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Axial Therapeutics, Inc. (US) | 2023-05-03 | — | — | EP | disclosed |
| US-20230051773-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AXIAL THERAPEUTICS, INC. (US) | 2023-02-16 | — | — | US | disclosed |
| WO-2021242923-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AXIAL THERAPEUTICS, INC. (US) | 2021-12-02 | — | — | WO | disclosed |
| CN-110183366-A | A method of carbonyl thioesters is inserted by alkene and is combined to sulfur ester | 中国科学院成都生物研究所 | 2019-08-30 | — | — | CN | disclosed |
| CN-102676280-B | Oil composition for automobile hydraulic shock absorber | CHINA NAT PETROLEUM CORP | 2015-05-27 | — | — | CN | disclosed |
| CN-101467276-A | Liquid crystalline rylene tetracarboxylic acid derivatives and use thereof | MAX PLANCK GESELLSCHAFT (DE) | 2009-06-24 | — | — | CN | disclosed |
| EP-0913459-B1 | Surfactants | XEROX CORP (US) | 2004-03-10 | — | — | EP | disclosed |
| US-6527981-B1 | Azole/amine oxide preservatives | LONZA INC. | 2003-03-04 | — | — | US | disclosed |
| US-5944650-A | PHOSPHOROUS MODIFIED POLYOXYETHYLENE GLYCOL | XEROX CORPORATION (US) | 1999-08-31 | — | — | US | disclosed |
| EP-0913459-A1 | Surfactants | Xerox Corporation (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0563281-B1 | METHOD FOR PROCESSING ELECTRICALLY CONDUCTIVE POLYANILINES IN LEWIS-BASE SOLVENTS | MONSANTO CO (US) | 1998-08-05 | — | — | EP | disclosed |
| EP-0563281-A1 | METHOD FOR PROCESSING ELECTRICALLY CONDUCTIVE POLYANILINES IN LEWIS-BASE SOLVENTS | AlliedSignal Inc. (US) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011645-A1 | METHOD FOR PROCESSING ELECTRICALLY CONDUCTIVE POLYANILINES IN LEWIS-BASE SOLVENTS | ALLIED-SIGNAL INC. (US) | 1992-07-09 | — | — | WO | disclosed |
| US-3988378-A | ANTISTATIC AGENTS, STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3936422-A | Anti-static modified thermoplastics | CIBA-GEIGY CORPORATION (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230051773-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | TLR2, TLR3, TLR4 | KCNH2 4714/4885DNM1 4144/4885EPHX2 3924/4885 |
| US-20240156780-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | TLR2, TLR3, TLR4 | KCNH2 4714/4885DNM1 4144/4885EPHX2 3924/4885 |
| US-11951094-B2 | TLR2 modulator compounds, pharmaceutical compositions and uses thereof | TLR2, TLR3, TLR4 | KCNH2 4714/4885DNM1 4144/4885EPHX2 3924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.