Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Hydrazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL22829518 | 1.00 | — | — | |
| Hydrazine SCHEMBL543699 | 1.00 | — | — | |
| Hydrazine SCHEMBL598082 | 1.00 | — | — | |
| Hydrazine SCHEMBL22829519 | 1.00 | — | — | |
| Hydrazine SCHEMBL1639413 | 0.87 | — | — | |
| Hydrazine SCHEMBL14859445 | 0.87 | — | — | |
| Hydrazine SCHEMBL4307 | 0.87 | — | — | |
| Hydrazine SCHEMBL14860255 | 0.87 | — | — | |
| Hydrazine SCHEMBL21541663 | 0.87 | — | — | |
| Hydrazine SCHEMBL6359434 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186596-B1 | PROCESS FOR THE PRODUCTION OF 2-PYRIDYLPYRIDINE DERIVATIVES | SANKIO CHEMICAL CO LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6504032-B1 | Forming 2,4'-, 2,3'- or 2,2'-dipyridyl's, by reacting 1,2,4-triazines, nitriles and hydrazines, then with glyoxal and finally with 2,5-norbornadiene; cylization; by product inhibition | SANKIO CHEMICAL CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| EP-1186596-A1 | PROCESS FOR THE PRODUCTION OF 2-PYRIDYLPYRIDINE DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-03-13 | — | — | EP | disclosed |