Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873585 | 0.81 | MCHR1 (0.42) | MCHR1HRH3 | |
| SCHEMBL5873663 | 0.80 | MCHR1 (0.63) | MCHR1NPC1RAB9A | |
| SCHEMBL6557970 | 0.79 | MCHR1 (0.59) | MCHR1HRH3 | |
| SCHEMBL6559810 | 0.77 | MCHR1 (0.42) | MCHR1HRH3PLAU | |
| SCHEMBL5873732 | 0.77 | MCHR1 (0.43) | MCHR1HRH3 | |
| SCHEMBL6557606 | 0.74 | MCHR1 (0.47) | MCHR1HRH3 | |
| SCHEMBL5873704 | 0.74 | MCHR1 (0.62) | MCHR1NPC1RAB9A | |
| SCHEMBL5873484 | 0.71 | MCHR1 (0.79) | MCHR1 | |
| SCHEMBL5873621 | 0.71 | MCHR1 (0.56) | MCHR1HRH3NPC1RAB9A | |
| SCHEMBL5873617 | 0.71 | MCHR1 (0.56) | MCHR1HRH3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450801-A2 | 2-AMINOQUINOLINE COMPOUNDS | Merck & Co., Inc. (US) | 2004-09-01 | — | — | EP | claimed |
| WO-2003045313-A2 | 2-AMINOQUINOLINE COMPOUNDS | MERCK & CO. INC. (US) | 2003-06-05 | — | — | WO | claimed |