SCHEMBL6560040

SCHEMBL6560040

CCCCCNc1ccc2cc(NC(=O)CCc3ccc(C(F)(F)F)cc3)ccc2n1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5873608 0.85 MCHR1 (0.78) MCHR1
SCHEMBL5873633 0.83 MCHR1 (0.81) MCHR1
SCHEMBL5873592 0.83 MCHR1 (0.74) MCHR1
SCHEMBL5873545 0.82 MCHR1 (0.77) MCHR1
SCHEMBL5873717 0.82 MCHR1 (0.77) MCHR1
SCHEMBL5873614 0.82 MCHR1 (0.77) MCHR1
SCHEMBL5873723 0.81 MCHR1 (0.78) MCHR1
SCHEMBL5873754 0.79 MCHR1 (1.00) MCHR1
SCHEMBL5873603 0.79 MCHR1 (0.74) MCHR1
SCHEMBL5873636 0.78 MCHR1 (0.87) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1450801-A2 2-AMINOQUINOLINE COMPOUNDS Merck & Co., Inc. (US) 2004-09-01 EP claimed
WO-2003045313-A2 2-AMINOQUINOLINE COMPOUNDS MERCK & CO. INC. (US) 2003-06-05 WO claimed