Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873502 | 0.83 | MCHR1 (0.65) | MCHR1MAPTPOLB | |
| SCHEMBL5873505 | 0.83 | MCHR1 (0.65) | MCHR1MAPTPOLB | |
| SCHEMBL5873514 | 0.82 | MCHR1 (0.65) | MCHR1 | |
| SCHEMBL5873521 | 0.82 | MCHR1 (0.65) | MCHR1 | |
| SCHEMBL5873590 | 0.81 | MCHR1 (0.73) | MCHR1 | |
| SCHEMBL6311117 | 0.80 | MCHR1 (1.00) | MCHR1MCHR2 | |
| SCHEMBL6203999 | 0.80 | MCHR1 (1.00) | MCHR1MCHR2 | |
| SCHEMBL6198980 | 0.78 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL6198991 | 0.78 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL6199666 | 0.75 | MCHR1 (1.00) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450801-A2 | 2-AMINOQUINOLINE COMPOUNDS | Merck & Co., Inc. (US) | 2004-09-01 | — | — | EP | claimed |
| WO-2003045313-A2 | 2-AMINOQUINOLINE COMPOUNDS | MERCK & CO. INC. (US) | 2003-06-05 | — | — | WO | claimed |