Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873628 | 0.94 | MCHR1 (0.53) | MCHR1SMN1; SMN2GAATSHRMAPT | |
| SCHEMBL5873534 | 0.82 | MCHR1 (0.56) | MCHR1SMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL5873663 | 0.82 | MCHR1 (0.63) | MCHR1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL5873516 | 0.79 | MCHR1 (0.55) | MCHR1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL5873615 | 0.78 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL5873550 | 0.78 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL5873575 | 0.76 | MCHR1 (0.55) | MCHR1SMN1; SMN2GAATSHRMAPT | |
| SCHEMBL5873704 | 0.76 | MCHR1 (0.62) | MCHR1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL5873688 | 0.76 | MCHR1 (0.55) | MCHR1SMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL5873481 | 0.76 | MCHR1 (0.55) | MCHR1SMN1; SMN2RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450801-A2 | 2-AMINOQUINOLINE COMPOUNDS | Merck & Co., Inc. (US) | 2004-09-01 | — | — | EP | claimed |
| WO-2003045313-A2 | 2-AMINOQUINOLINE COMPOUNDS | MERCK & CO. INC. (US) | 2003-06-05 | — | — | WO | claimed |