Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | PPARD | Q03181 | 8/20 | 0.42 |
| ▸ | PPARA | Q07869 | 8/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560087 | 0.94 | PPARG (0.43) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6560686 | 0.85 | PPARG (0.41) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6560623 | 0.85 | PPARD (0.47) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6560640 | 0.79 | PPARG (0.42) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL8444011 | 0.76 | PPARG (0.42) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6934155 | 0.73 | PPARG (0.65) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL8439203 | 0.72 | PPARG (0.52) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6939961 | 0.72 | PPARG (0.49) | PPARGPPARDPPARA | |
| SCHEMBL7043241 | 0.71 | PPARG (0.74) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL7044053 | 0.71 | PPARA (0.67) | PPARGPPARDPPARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | disclosed |
| US-5859051-A | ACETYLPHENOL DERIVATIVES | MERCK & CO., INC. (US) | 1999-01-12 | — | — | US | disclosed |