Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HMGCR | P04035 | 6/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139739 | 1.00 | RECQL (0.63) | RECQLTDP1PTPN7POLBMAPT | |
| SCHEMBL6560559 | 1.00 | RECQL (0.63) | RECQLTDP1PTPN7POLBMAPT | |
| SCHEMBL6560232 | 1.00 | RECQL (0.63) | RECQLTDP1PTPN7POLBMAPT | |
| SCHEMBL6559624 | 1.00 | RECQL (0.63) | RECQLTDP1PTPN7POLBMAPT | |
| SCHEMBL7135999 | 1.00 | RECQL (0.63) | RECQLTDP1PTPN7POLBMAPT | |
| SCHEMBL6560234 | 0.98 | PTPN7 (0.62) | RECQLTDP1PTPN7POLBMAPT | |
| SCHEMBL7135940 | 0.98 | PTPN7 (0.62) | RECQLTDP1PTPN7POLBMAPT | |
| SCHEMBL6559580 | 0.97 | PTPN7 (0.60) | RECQLTDP1PTPN7POLBMAPT | |
| SCHEMBL4661904 | 0.95 | HMGCR (0.59) | RECQLTDP1PTPN7POLBMAPT | |
| SCHEMBL6561960 | 0.95 | HMGCR (0.59) | RECQLTDP1PTPN7POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044966-B1 | (Poly)thia-alkyne compounds and their derivatives, compositions containing them and their use | OREAL (FR) | 2004-09-22 | — | — | EP | claimed |
| US-6511670-B1 | Compounds with shorter alkyl chains such as 3,8-dithia-5-docosynoic acid; treating acne and inflammation disorders; peroxisome proliferator activated receptor activators | SOCIETE L'OREAL S.A. (FR) | 2003-01-28 | — | — | US | claimed |
| US-6511670-B1 | Compounds with shorter alkyl chains such as 3,8-dithia-5-docosynoic acid; treating acne and inflammation disorders; peroxisome proliferator activated receptor activators | SOCIETE L'OREAL S.A. (FR) | 2003-01-28 | — | — | US | disclosed |